The head of the conidia is rough, hemispherical and radial. The conidia are colorless or yellowish, thick and smooth.
The parietal capsule is semi-elliptical to hemispherical, and the parietal capsule has a double-layer small stem. ? The conidia are spherical, have small spines, and are chain-like variegated aspergillus
Produced by Aspergillus versicolor, it is a class of toxins with similar chemical structure, in which aspergillus versicolor IVa is the most important
The main one is light yellow needle crystal.
Aspergillus variegated has acute, chronic toxicity and carcinogenicity, mainly damages the liver and kidney. Microbiological inspection
(1) Direct microscopy
Sputum and other test materials are coated on a glass slide. Branched hyphae and thicker conidia can be seen under the microscope
The head is swollen at the top to form a parietal sac. There are small stems on the top sac, and there are many small conidia on the small stems.
(2) Antigen detection Competitive ELISA was used to determine the Aspergillus antigen in the serum of patients. (3) Isolation, culture and identification of specimens inoculated with Sarger's agar. After incubation at room temperature, the colony formed quickly and was hairy, generally yellow-green. Microscopic examination of colony smears revealed characteristic molecular spore heads and podocytes. (4) The drug sensitivity test is sensitive to nystatin and amphotericin B.
(5) Antibody detection Detects anti-Aspergillus antibodies in the patient's serum. Commonly used immunodiffusion detection, which has high sensitivity and specificity, can also be used convection immunoelectrophoresis, ELISA, biotin-avidin-linked immunosorbent assay (BALISA), radioimmunoassay (RIA) and indirect immunofluorescence. Mycelium and culture filtrate can be used as ELISA antigen.
(6) Skin test Aspergillosis antigen extract can be used as a skin test for patients with allergic bronchopneumonia.
Type â… hypersensitivity reactions occur positively within 15-20 minutes. Type â…¡ hypersensitivity reaction appeared positive in 4-10h.
Type â…£ hypersensitivity can occur in patients with hypersensitivity pneumonia.
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