Recently in the Netherlands, researchers at the University of Groningen have developed a 3D-printable antimicrobial plastic that is used primarily in the photocuring process. When it is placed together with a saliva sample, it can effectively kill more than 99% of Streptococcus mutans, which is the main culprit causing people to tooth decay.
According to the National Institute of Dental and Craniofacial Research, dental caries are the most common chronic disease in both children and adults, although it is preventable. However, gum disease is a constant threat to people who are diligent in brushing their teeth and flossing twice a day. To make matters worse, in many parts of the world, people do not have healthy oral hygiene practices and do not have reliable oral care. If left unchecked, oral diseases tend to be more or less associated with heart disease, stroke, diabetes, and even dementia. So is there a way for our teeth to have the ability to kill the bacteria that cause tooth decay? Have! A new 3D printed material that can be used to make teeth and braces has this capability.
It is known that this material is made by incorporating an antibacterial quaternary ammonium salt into an existing dental resin polymer. This salt is positively charged, so it can destroy negatively charged bacteria, causing them to "explode and die" once they come into contact. At the same time, this material is completely harmless to human cells. In controlled control samples, materials that did not contain such positively charged quaternary ammonium salts killed less than one percent of harmful bacteria.
The researchers put a mixture of salt and photopolymer into a photocuring 3D printer to print a series of dental objects, such as dentures and orthodontic braces, and then perform the above tests. Researchers say their next study will extend it to all oral hygiene products, such as toothpaste, braces, etc., so that everyone can benefit from oral cleansing.
Andreas Hermann, one of the researchers at the project, said that they still need to conduct further tests to ensure that the material is strong enough to be used as a real tooth. In the current study, their method was to mix the tested samples of 3D printed materials with saliva and bacteria for six days, and future researchers will try to experiment in different time periods to assess the time factor for The effect of the results, and whether the material can be used in products such as toothpaste. However, he expects these studies to be able to get results soon: "This is a medical product that is foreseen to be applied soon in the near future, much less time than developing a new drug."
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